Anders Nilsson

Anders Nilsson

We are studying the complex genome evolution of bacteriophages and their coevolution with bacteria. The amount of genetic variation among phages is greater than within any other group of organisms. The genomes of many phages are made up of interchangeable modules which can be horizontally transferred between genomes. Phages can also pick up genes from one bacterium and deliver them to another, which makes them a very important factor in the evolution of bacteria. Alike other host-parasite systems, phages have evolved different levels of virulence. Some phages are extremely virulent and instantly kill their host while others have the ability to integrate into the bacterial genome and establish a mutualistic relationship with their host.

TEM-F566K

The evolution of P2-like bacteriophages

P2-like phages are a group of temperate phages infecting gamma-proteobacteria. In addition to the ability to lyse and kill their host, these phages can also integrate into the bacterial host genome and stay as a prophage awaiting a better opportunity to reproduce.

KPN557 F557K 100401

Phage therapy - an effective method to fight multiresistant bacteria.

Bacteriophages are viruses that infect, reproduce, and eventually kill bacteria. They are very common in nature, and play an important role in bacterial ecosystems. Due to a huge genetic variation, there are always phage clones in nature that are able to lyse and kill a certain bacterium.

Contact

Anders

Anders Nilsson, Assistant professor
e-mail: anders.nilsson@gmt.su.se
Telephone: +46-8-16 4549
Fax:+46-8-16 4315

Visiting address
Svante Arrhenius väg 20C floor 5 room 547

Postal address
Department of Genetics, Microbiology and Toxicology
Stockholms Universitet
106 91 Stockholm

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